Realistically, I'd think the standard for cars will be like 100mpg for new vehicles (it's at 35mpg ATM in the US and is about to rise), but most commuters will most likely be motorcyclists or have self-driving micro-cars due to traffic standards.
Extreme weather conditions due to pollution and ozone degradation
Cure for aids and several forms of cancer, but new super anti-biotic resistant strains will emerge due to overuse
Technology will probably lead to the introduction of Solid State Drives capable of storing memory in the Petabyte range available to consumers with 16gb Ram cards being the cheapest standard going up all the way to 128gb
Just a guess